Unmiraculous facultative anaerobes (comment on DOI 10.1002/bies.201600174).

نویسنده

  • William F Martin
چکیده

ry In a recent paper in these pages, Speijer [1] contends that anaerobic, aerobic metabolism cannot exist within the same organism. In particular he argues that anaerobic, aerobic metabolism cannot exist within the same eukaryote. He also contends that this argument constitutes evidence against the view that mitochondria are ancestrally facultatively anaerobic. However, he neglects the literature on prokaryotic, eukaryotic facultative anaerobes, so a short reply is in order. The strongest argument that Speijer can muster against the view that the ancestral mitochondrion (or ancestral eukaryotes) were facultative anaerobes is found in his section entitled “Problems with assuming hydrogen exchange.” There he writes “But how could the future endosymbiont have retained its complex multi-subunit aerobic respiratory chain under prolonged anoxic conditions? Do not prokaryotes rapidly lose what they do not use?” (emphasis from the original). According to that argument, no facultative anaerobes, either prokaryotic or eukaryotic, should exist at all. Chlamydomonas reinhardtii should not exist, because it is a facultative anaerobe [2], nor should Euglena gracilis exist, because it is also a facultative anaerobe [3, 4], nor should other biochemically well-studied eukaryotes exist that use their mitochondria to survive with or without oxygen [5, 6]. Indeed, according to Speijer’s strongest argument, Escherichia coli, which is an excellent facultative anaerobe [7], should not exist either, nor should alpha-proteobacteria in general, most of which are in fact

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Is anti‐viral defence the evolutionary origin of mRNA turnover? (Comment on DOI 10.1002/bies.201600100)

In this issue of BioEssays, Hamid and Makeyev explore an interesting new idea regarding the evolutionary origins of regulated mRNA turnover pathways [1]. One such pathway is nonsensemediated decay (NMD) that detects and targets for degradation a subset of mRNAs including transcripts with premature translation termination codons. The authors develop a model in which these pathways initially evol...

متن کامل

Effects of hyperbaric oxygen on aggressive periodontitis and subgingival anaerobes in Chinese patients

OBJECTIVE To investigate the effects of hyperbaric oxygen (HBO2) on aggressive periodontitis (AgP), and subgingival obligate anaerobes in Chinese patients. MATERIALS AND METHODS Sixty cases of Chinese patients with AgP were randomly divided into two groups -the HBO2 group (30 cases) and the control group (30 cases). Study teeth were divided into four groups -: the HBO2 therapy, the HBO2 + sca...

متن کامل

Comment on "Does constructive neutral evolution play an important role in the origin of cellular complexity?" DOI 10.1002/bies.201100010.

Speijer [1] has provided a critique of constructive neutral evolution (CNE) and its role in the origin and evolution of cellular complexity [2, 3]. Not surprisingly, we disagree with his assertions. Because his description of the CNE model does not precisely conform to our view of CNE, as we [2, 4] and Stoltzfus [3] have elaborated it, we briefly re-state the model before addressing Speijer’s o...

متن کامل

Predation between prokaryotes and the origin of eukaryotes.

Accumulating data suggest that the eukaryotic cell originated from a merger of two prokaryotes, an archaeal host and a bacterial endosymbiont. However, since prokaryotes are unable to perform phagocytosis, the means by which the endosymbiont entered its host is an enigma. We suggest that a predatory or parasitic interaction between prokaryotes provides a reasonable explanation for this conundru...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • BioEssays : news and reviews in molecular, cellular and developmental biology

دوره 39 6  شماره 

صفحات  -

تاریخ انتشار 2017